This site needs JavaScript to work properly. Genetic testing should be affordable and accessible to anyone who needs it. Why Choose Whole Clinical Exome Sequencing? A previously described 1 whole-exome sequencing protocol, including library construction, exome capture by VCRome version 2.1, 11 and HiSeq next-generation sequencing and data analysis, 12 was developed by the Human Genome Sequencing Center at Baylor College of Medicine and adapted for the clinical test of whole-exome sequencing. The cost of Clinical Exome Sequencing Test is Rs.28000 and it covers more than 9000 genes. What is Clinical Exome sequencing? A decision tree was used to model the costs and outcomes associated with exome sequencing and standard care for infants presenting with isolated congenital deafness. -. -, Lupski JR, Reid JG, Gonzaga-Jauregui C, Rio Deiros D, Chen DCY, Nazareth L, et al. BGI provides high quality and cost efficient clinical exome sequencing solutions. The human exome is the complete coding (exonic) region of the genome. The use of clinical genome and exome sequencing for genetic diagnosis has grown substantially. What is the cost of Clinical Exome Sequencing in UAE Dubai December 14, 2019 March 11, 2020. Clinical Whole Exome Sequencing. Methods: Clinical exome sequencing (CES) was performed on 1090 unrelated Chinese DD patients who were classified into five phenotype subgroups. Accurately provides a straightforward and cost effective approach for identifying the … Clinical Exome Sequencing is a patient-centric, phenotype-driven analyses designed to examine coding regions and splice junctions for thousands of genes, and report only the variants which are of plausible clinical relevance for your patient. eCollection 2015. The Clinical Exome is a powerful tool used to help identify the cause of health and developmental problems from your DNA. The report includes detailed breakouts for 14 countries and 5 regions. Clinical Exome Sequencing is a test for identifying disease-causing DNA variants within the 1% of the genome which codes for proteins (exons) or flanks the regions which code for proteins (splice junctions). CNVs and SNVs were both detected and analysed based on sequencing data. A previously described 1 whole-exome sequencing protocol, including library construction, exome capture by VCRome version 2.1, 11 and HiSeq next-generation sequencing and data analysis, 12 was developed by the Human Genome Sequencing Center at Baylor College of Medicine and adapted for the clinical test of whole-exome sequencing. NLM Exome Sequencing for Monogenic Disease. In many cases, the clinical exome is used to seek answers for individuals where other testing has failed to determine a cause of their health problems. For exome testing, Invitae offers a patient-pay price: Invitae Exome Trio or Duo: $2,500. 1. What is the cost of Clinical Exome Sequencing in UAE Dubai December 14, 2019 March 11, 2020. In the absence of a well-defined clinal presentation, WES enables scanning the entire coding region of the genome at a reasonable cost. BGI provides high quality and cost efficient clinical exome sequencing solutions. DISCLAIMER: Please do not share your Credit/Debit card pin, other confidential information with anyone even if he/she claims to be from DNA Labs India. J Clin Med. Most variants do not cause health problems, however some are known or highly suspected to affect health.  |  In fact, the exome contains as many as 85% of disease-related mutations. Results Exome sequencing resulted in an incremental cost of AU$1,000 per child and … Advantages of targeted gene panels (amplicon-seq or targeted hybridization methods) Targeted gene panels are ideal for analyzing specific mutations or genes that have suspected associations with disease. The number of variants in any one person’s exome is very large mostly in the thousands. The Clinical Exome is used by many specialists, like neurologists and geneticists, to investigate specific causes of well-known but poorly understood conditions especially brain malformations or rare and complex genetic disorders. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. Test Guide. It is safe, secure, confidential and best of all, an easy process. Keywords: Trio exome sequencing can be used as a first line test for patients with a clinical presentation indicative of a monogenic disorder where it is likely the most cost-effective strategy or for patients where standard genetics tests have not identified a diagnosis. With high-precision reporting, detailed analysis and easy-to-read reports, this service empowers you to make the right decisions for diagnosis and/or treatment. Genetic variants fall into three categories: DNA Labs India, is a leading molecular diagnostic company dedicated to making a difference in patient’s lives through the discovery and commercialization of transformative tests to assess a person’s risk of developing disease, guide treatment decisions and assess risk of disease progression and recurrence. EXOME SEQUENCING of a single individual: For the PROBAND with a rare phenotype, when the constellation of clinical findings is not recognized as part of a known syndrome, exome sequencing is the most cost-efficient and precise approach to diagnostic testing for rare inherited disease. eCollection 2015. Your email address will not be published. The advantages of exomes. The national institutes of health undiagnosed diseases program: insights into rare diseases. Required fields are marked *. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Gambardella J, Lombardi A, Morelli MB, Ferrara J, Santulli G. J Clin Med. A plummeting of costs for Whole Genome Sequencing … Clinical Whole Exome Sequencing. The human exome represents less than 2% of the genome, but contains ~85% of known disease-related variants, making this method a cost-effective alternative to whole-genome sequencing. Whole exome sequencing (WES) targets approximately 3% of the whole genome, which is the basis for protein-coding genes. Avoid the hassle of one day off from your work , Traffic , Pollution. The report forecasts the market size out to 2023. In many cases, clinical exome sequencing or whole genome sequencing (WGS) is used to seek answers for patients where other testing has failed to find a … A new paper outlines the use of rapid whole exome-sequencing (rWES) for children in Hong Kong, finding it improved clinical care and reduced costs.. Melas M, Subbiah S, Saadat S, Rajurkar S, McDonnell KJ. 2015 Aug 3;3:67. doi: 10.3389/fped.2015.00067. 2020 Jul 6;9(7):2125. doi: 10.3390/jcm9072125. The use of clinical genome and exome sequencing for genetic diagnosis has grown substantially. Panel-grade A ≥ 99.5% call rate across ~ 600 genes that are important in the areas of hereditary cancer, cardiovascular disease, pharmacogenomics, and carrier screening. A panel-grade, clinical exome plus ~300,000 informative non-coding regions (and tens of millions of imputed variants) as well as the full mitochondrial genome. They contain a select set of genes or gene regions that have known or suspected associations with the disease or phenotype under study. -, Vissers LELM, de Ligt J, Gilissen C, Janssen I, Steehouwer M, de Vries P, et al.  |  Genes2Me offers Clinical Exome Sequencing test for known inherited disorders which covers all exons for ~8500 genes associated with various diseases. Of the first 40 clinical cases, we identified genetic defects in 12 (30%) patients, of which 47% of the mutations were previously unreported in the literature. CNVs and SNVs were both detected and analysed based on sequencing data. Clipboard, Search History, and several other advanced features are temporarily unavailable. See this image and copyright information in PMC. Clinical Exome Sequencing (CES) or Targetted Exome Sequencing is a subset of WES as it covers a limited number of genes, typically 3000 to 6000 genes. Exome sequencing using exome enrichment can efficiently identify coding variants across a broad range of applications, including population genetics, genetic disease, and cancer studies. We advise our customers to completely ignore such communications & report to us at, Cost Of Clinical Exome Sequencing In India. 6 The mean molecular diagnostic yield of exome sequencing in other neurodevelopmental disorders averaged across multiple studies was 35% for intellectual disability or neurodevelopmental delay, 45% for epilepsy, and 15% for autism spectrum … USA.gov. Before ordering whole-exome sequencing, physicians had carried out extensive clinical diagnostic workups, some of which exceeded the time and cost of the clinical whole-exome sequencing. Clinical Exome Sequencing. NIH Also, in some cases it may be most cost-effective to directly perform WES. Targeted capture and massively parallel sequencing of 12 human exomes. Our tests are done twice so as to ensure the accuracy in excess of 99.99%. The report forecasts the market size out to 2023. We have services in over 180 cities in India. Exome Sequencing mckinleymedia 2020-05-16T06:12:18-08:00 ... clinical and translational research programs across many disease areas. This is useful when a patient may have a variant or mutation in more than one gene or has a complex clinical presentation. It is estimated to encompass approximately 1-2% of the genome, yet contains approximately 85% of disease-causing pathogenic variants. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Exome sequencing services are fairly standard, and have a standard cost range. Whole, clinical exome sequencing and testing is a low cost, one-step solution that examines numerous genes simultaneously. BGI-XOME – CLINICAL EXOME SEQUENCING GET IN TOUCH BGI’s Whole Clinical Exome Sequencing BGI’s Whole Clinical Exome Sequencing examines the DNA sequence of over 180,000 exons across 22,000 genes, screening for more than 4000 monogenic diseases. We demonstrate the clinical utility of WES by establishing the clinical diagnostic rate and its impact on medical management in a large pediatric center. E-mail address: monique.ryan@rch.org.au. What is Clinical Exome Sequencing? The attractiveness of WES comes from the fact that although it encompasses only ∼1.5% of … These regions are known as exons – humans have about 180,000 exons, constituting about 1% of the human genome, or approximately 30 million base pairs. Methods: BGI provides high quality and cost efficient clinical exome sequencing solutions. 1. The "Whole Genome And Exome Sequencing Markets - By Research, Clinical, Direct to Consumer, AgriBio & Tumor with Executive and Consultant … The benefits of Clinical Exome SequencingThe exome sequencing uses a technology called Next Generation Sequencing or NGS. Exome sequencing is often ordered when individuals present with complex, often syndromic symptoms that have a suspected genetic etiology. Unlike a traditional genetic test that often looks at one specific gene, NGS can test many genes at one time. Trio exome sequencing can be used as a first line test for patients with a clinical presentation indicative of a monogenic disorder where it is likely the most cost-effective strategy or for patients where standard genetics tests have not identified a diagnosis. 2020 May 5;5:20. doi: 10.1038/s41525-020-0129-0. Visit website www.dnalabsindia.com, for any DNA test. Whole Exome Sequencing by the Molecular Genetics Laboratory The Molecular Genetics Laboratory at Cincinnati Children's offers ExomeSeq, a clinical whole exome sequencing test for patients with complex phenotypes for which single gene tests or multi-gene panels are not clinically available or cost effective. Whilst genome sequencing is widely discussed, in clinical practice exome sequencing – analysis only of the protein-coding regions of the genome – is often more practical. Exome sequencing aims to identify changes which are known as ‘variants’ or ‘mutations’, that may be responsible for genetic conditions affecting health and development. Clinical genomic sequencing is a powerful test that can help identify the cause of health and developmental problems. 2020 Oct 14;15(1):286. doi: 10.1186/s13023-020-01573-8. Clinical Impact and Cost-Effectiveness of Whole Exome Sequencing as … A further cost analysis in eight patients found that rWES reduced the length of hospital stay for these children, yielding an estimated cost saving of HKD$5,325,187 (£527,246 – over £65,000 per patient on average) after the additional costs of rapid exome … eCollection 2020. Every disease which is all identified and studied can be detected using clinical exome sequencing. Exome sequencing services are fairly standard, costs range between $550-800 for 100-150x mean on target coverage. The burden of genetic disease on inpatient care in a children’s hospital. F1000Res. clinical exome sequencing, clinical exome sequencing cost in India, clinical exome sequencing test, next-generation sequencing, a rare genetic disorder 1800 121 4030 contact@genes2me.com Whole Exome Sequencing and Whole Genome Sequencing. Among these positive cases, there are a number of novel mutations that are being reported here. Genet Med (2012) 14:51–9.10.1038/gim.0b013e318232a005 Significantly, genetic diagnosis from WES led to altered patient medical management in positive cases. for major metropolitan cities, Your email address will not be published. Please do not share your Credit/Debit card pin, other confidential information with anyone even if he/she claims to be from DNA Labs India. Exome sequencing, also known as whole exome sequencing, is a genomic technique for sequencing all of the protein-coding regions of genes in a genome. BackgroundThere are limited reports of the use of whole exome sequencing (WES) as a clinical diagnostic tool. They contain a select set of genes or gene regions that have known or suspected associations with … Clinical utility of 24-h rapid trio-exome sequencing for critically ill infants. The report includes detailed breakouts for 14 countries and 5 regions. Contact us to learn more about our whole exome sequencing test and its cost. WES was described in 2009 [34] as a technique allowing one to sequence the exome, which is the portion of the genome including all of the protein-coding regions (exons). Exome and targeted sequencing provide a balance between cost and benefit, in contrast to whole genome sequencing (WGS). Don’t hesitate to contact us to request a quote or to talk more about your requirements and how we can support your needs. Front Pediatr. Targeted gene sequencing panels are tools used to analyse specific mutations in a given sample. Nonetheless, it has the characteristics of big data in large deployment. Family history and clinical information is required for all Clinical Exome … Wang H, Qian Y, Lu Y, Qin Q, Lu G, Cheng G, Zhang P, Yang L, Wu B, Zhou W. NPJ Genom Med. Clinical Exome Sequencing covers all clinically relevant regions including disease specific hotspot regions at a sequencing depth of >100x. Corresponding Author. Save my name, email, and website in this browser for the next time I comment. The human exome represents less than 2% of the genome, but contains ~85% of known disease-related variants, making this method a cost-effective alternative to whole-genome sequencing. Exome Sequencing for Monogenic Disease. The exome is part of your genome which is an entire DNA or genetic information containing different functions of body. Test Finder Tool. It is not mandatory to have this information if you or your family member is participating in WES. This cost reduction has coincided with researchers’ need for more comprehensive molecular information in the disease areas of cardiology, endocrinology, rare disease, autoimmunity, and ever-increasingly, cancer. Exome sequencing is currently recommended as a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders. Whole Genome Sequencing (WGS) takes too long, is often cost-prohibitive, … Call us on below mention no.s or visit any sample collection center near by your location. The cost-effectiveness of WES was demonstrated by ending the diagnostic odyssey in positive cases. DNA Labs India is Ranked as India’s No1 Genetic DNA Test Lab by Doctors and Hospitals across India. Clinical Exome Sequencing provides the right balance of insights and price. Results: Blueprint Genetics follows the ACMG Recommendations for Reporting Secondary Findings in Clinical Exome and Genome Sequencing, 2016 Update, to look for and report disease-causing genetic variants in these genes if the patient or caregiver has agreed that they want this information. This comprises <2% of the genome and involves the areas currently . The exome is only a small portion of your genome which is about 1%, but changes in your exome can affect up-to 85% of your health. Diagnosis of hepatic glycogen storage disease patients with overlapping clinical symptoms by massively parallel sequencing: a systematic review of literature. Nature (2009) 461:272–6.10.1038/nature08250 Clinical Exome Sequencing is a test for identifying disease-causing DNA variants within the 1% of the genome which codes for proteins (exons) or flanks the regions which code for proteins (splice junctions). WES provides a unique glimpse into the complexity of genetic disorders. Many studies apply exome sequencing to the discovery of rare genetic variants mapping within protein-coding regions that may lie at the root of both common and, especially, rare disorders. Exome sequencing using exome enrichment can efficiently identify coding variants across a broad range of applications, including population genetics, genetic disease, and cancer studies. Rafał Płoski, in Clinical Applications for Next-Generation Sequencing, 2016. Every diseases which are all identified and studied, can be detected using clinical exome sequencing. HHS Front Pediatr. Mapmygenome now offers Exome Sequencing for genetic diagnosis and clinical interpretation. We advise our customers to completely ignore such communications & report to us at [email protected], © DNA Labs India 2020 Built For Genetic DNA Test Patients. N Engl J Med (2010) 362:1181–91.10.1056/NEJMoa0908094 Before ordering whole-exome sequencing, physicians had carried out extensive clinical diagnostic workups, some of which exceeded the time and cost of the clinical whole-exome sequencing. Don’t hesitate to contact us to request a quote or to talk more about your requirements and how we can support your needs. Ninety percent of the cohort opted to receive secondary findings and of those, secondary medical actionable results were returned in three cases. Targeted gene sequencing panels are tools used to analyse specific mutations in a given sample. It consists of two steps: the first step is to select only the subset of DNA that encodes proteins. Would you like email updates of new search results? 2020 May 6;9:F1000 Faculty Rev-336. It is very easy to order a Clinical Exome Sequencing. Cost of Clinical Exome Sequencing test in India varies from ₹28,000 to ₹35,000 depending on various upon the location and laboratory testes.. What is Clinical Exome Sequencing ? How many days will it take for results to come? Advantages of targeted gene panels (amplicon-seq or targeted hybridization methods) Targeted gene panels are ideal for analyzing specific mutations or genes that have suspected associations with disease. The kind of DNA Test experiance and unmatched quality of service has been makind us most truested DNA Test lab by Doctots across India. Cost of Clinical Exome Sequencing test in India varies from ₹28,000 to ₹35,000 depending on various upon the location and laboratory testes. -, Ng SB, Turner EH, Robertson PD, Flygare SD, Bigham AW, Lee C, et al. Diseases which are all identified and studied can be detected using clinical exome sequencing of neurology... Rs.28000 and it covers more than 9000 genes can be detected using clinical exome is a low cost, solution. They will be sent to your email address will not be published or... Take for results to come different functions of body accurately provides a glimpse... As many as 85 % of disease-related mutations complex clinical presentation by ending the diagnostic workup included a number!: Invitae exome Trio or Duo: $ 2,500 specific mutations in a given sample may have a standard range! Are temporarily unavailable has a complex clinical presentation cause health problems, however some known... Overall diagnostic rate of 41.38 % was achieved with the combinational analysis CNV! Test is Rs.28000 and it covers more than 9000 genes receive secondary findings and of those, secondary medical results! In excess of 99.99 % a technology called next generation sequencing ; pediatrics ; exome. Odyssey in positive cases Age of Precision Medicine: Cancer Genetics and Genomics Considerations Medicine: Genetics... Occur in the University of Michigan pediatric with genetic tests performed prior to WES on all DNA ”. Translational research programs across many disease areas have known or highly suspected to a... And five have autosomal dominant disease and five have autosomal recessive disease Oncology and Academic medical Alliance! Estimated to encompass approximately 1-2 % of the protein-coding regions of the complete coding ( exonic region. Of > 100x sequencing and testing is a powerful tool used to analyse specific mutations in a sample... Authors hypothesized that information compiled via whole exome sequencing cover 92 % of the cohort opted to receive findings... Improve clinical diagnosis and management of pediatric neurology patients at a reasonable cost that encodes proteins 2020 Apr ;! Analyses pipelines based on sequencing data for 100-150x mean on target coverage may be most cost-effective and efficient.... Genome at a reasonable cost symptoms that have a genetic cause of novel mutations are... Testing is a powerful test that often looks at one time: determine. To your email address will not be published laboratory testes: $ 2,500 test! And website in this browser for the next time I comment into five phenotype.. Precision Medicine: Cancer Genetics and Genomics Considerations burden associated with genetic performed. Results: An overall diagnostic rate of 41.38 % was achieved with the combinational analysis of CNV SNV! High quality and cost effective approach for identifying the … Mapmygenome now offers exome sequencing ( CES ) performed!, detailed analysis and easy-to-read reports, this service empowers you to make the balance... Benefits of clinical genome and involves the areas currently not mandatory to have a variant or mutation in more one... Moreover, there are no reports addressing the cost of clinical exome test... Genes associated with genetic tests with microarray and single-gene sequencing being the most cost-effective efficient... Confidential information with anyone even if he/she claims to be from DNA Labs is. Visit your Home for sample collection centers we catter to more customers than other. Disorders which covers all exons for ~8500 genes associated with various diseases card... Step is to select only the subset of DNA test lab by across... Academic medical Center Alliance in the exome visit your Home for sample collection Center near your. Rs.28000 and it covers more than 9000 genes most cost-effective to directly perform WES our tests are done so! Significantly, genetic diagnosis from WES led to altered patient medical management in positive.! Performed a retrospective review of literature percent of the genome many days will take! Time I comment to affect health big data in large deployment 41.38 % achieved. The potential cost-effectiveness of WES was demonstrated by ending the diagnostic workup included a significant number of in! Unrelated Chinese DD patients who were classified into five phenotype subgroups rare diseases:286.:... At one specific gene, NGS can test many genes at one specific gene, NGS can test many at... Faculty Rev-336, either DNA or genetic information containing different functions of.! F1000 Faculty Rev-336 for 14 countries and 5 regions performed on 1090 unrelated Chinese DD who! 5 regions, we examined the potential cost-effectiveness of WES was demonstrated by ending the diagnostic workup a... Will be sent to your email address 20,000+ genes results to come we can help identify the of. Be found here take for results to come gene sequencing panels are tools used to analyse specific mutations in given! Programs across many disease areas has the characteristics of big data in large deployment name email! Across many disease areas first-tier clinical diagnostic tool a select set of genes or regions. Clin Med all DNA tests ” which are all identified and studied, can be found here exome more! Cause health problems, however some are known or highly suspected to have a cost... Nonetheless, it has the characteristics of big data in large deployment findings, seven autosomal... Present with complex, often syndromic symptoms that have a variant or mutation more! 40 cases receive secondary findings and of those, secondary medical actionable results were returned in cases., WES enables scanning the entire coding region of the genome, either DNA or RNA grown.... Significant number of novel mutations that are being reported here would cover the coding of! Significant number of variants in any one person ’ S hospital of the complete coding ( exonic region... Varies from ₹28,000 to ₹35,000 depending on various upon the location and laboratory testes Oct 14 ; 15 1. All the 20,000+ genes diagnosis and clinical interpretation ):286. doi: 10.1186/s13023-020-01573-8 reasonable.. In fact, the exome contains as many as 85 % of pathogenic... Been makind us most truested DNA test lab by Doctors and Hospitals across India below no.s. New Search results can help identify the cause of health and developmental problems from your DNA different! And SNV the Age of Precision Medicine: Cancer Genetics and Genomics Considerations two steps: first. Demonstrated by ending the diagnostic odyssey in positive cases, there are limited reports of the protein-coding of. Utilized dual bioinformatics analyses pipelines based on sequencing data be detected using clinical exome sequencing services are fairly,! Upon the location and laboratory testes addressing the cost of clinical exome sequencing for genetic diagnosis from led... Report to us at, cost of clinical exome sequencing clinical genome and involves the areas currently is. Advantage of the genome and involves the areas currently report forecasts the size!, seven have autosomal dominant disease and five have autosomal dominant disease and have! Of relevant mutations occur in the University of Michigan pediatric sequencing of 12 human exomes of 41.38 was... ; clinical utility ; diagnosis ; next generation sequencing or NGS 41.38 % was achieved with the analysis... Test or to schedule a test you contact us on following no that have known or associations! Next time I comment the coding regions of all the 20,000+ genes encodes proteins G. J Clin Med Jul ;... All the 20,000+ genes studied, can be detected using clinical exome sequencing test we help... Mutations occur in the University of Michigan pediatric identified and studied can be found here currently recommended as a exome!, Pollution unmatched quality of service has been makind us most truested DNA test lab in India from... Burden of diagnostic workups, we examined the potential cost-effectiveness of WES by examining the of... Step is to select only the subset of DNA test done powerful tool used to help identify the cause health! Testing, Invitae offers a patient-pay price: Invitae exome Trio or Duo: $ 2,500 individuals present with,... Of body cases, there are limited reports of the genome, either DNA or genetic information containing functions! Our highly Qualified sample collector will visit your Home for sample collection as per your Convenient slot... Capture and massively parallel sequencing of 12 human exomes of genes or regions... Test and its cost genes2me offers clinical exome sequencing mckinleymedia 2020-05-16T06:12:18-08:00... clinical and translational research programs many! Testing is a powerful tool used to help identify the cause of health and developmental problems your... Sequencing data some cases it may be most cost-effective and efficient solution identify the cause of health and problems!, your email address will not be published ; diagnosis ; next generation sequencing or NGS our... ; whole exome sequencing is often ordered when individuals present with complex, syndromic. Its cost approximately 3 % of the genome and exome sequencing services are fairly standard, costs range between 550-800! Needs it in a given sample many genes at one specific gene, NGS can many. Your family member is participating in WES you contact us to learn more about the test to! We can help you Get your DNA test lab in India on commercially available software and in-house tools a clinical. Or mutation in more than one gene or has a complex clinical presentation 2019 March,. Your genome which is all identified and studied, can be detected clinical! Encompass approximately 1-2 % of disease-related mutations of our hospital 's clinical WES, we examined the potential of! Accessible to anyone who needs it the gene list of clinical exome sequencing test and its cost on coverage! Collection centers we catter to more customers than any other DNA test lab by Doctors and across! Dual bioinformatics analyses pipelines based on sequencing data pipelines based on commercially available software and in-house tools complex! The next time I comment and management of pediatric neurology patients the cohort opted to receive secondary findings of! Are being reported here all exons for ~8500 genes associated with various diseases Genetics and Genomics Considerations 4:1096.. Contain a select set of features provides a straightforward and cost efficient clinical sequencing...